Chitomur
/ Khavinson-tradition urinary bladder muscle bioregulator (KE-class)ALIAS · Chitomur · Urinary muscle bioregulator
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Tier 4. The Russian-origin literature includes a single small Russian-language randomized blind clinical study in elderly women with hyperactive bladder (Gomberg 2013, Adv Gerontol). Sample size and methodology fall short of the standard expected for FDA review, and there is no independent Western replication.
Chitomur is presented within the Khavinson peptide-bioregulator framework as a short peptide preparation targeting urinary bladder smooth muscle. The class-level mechanistic hypothesis is sequence-specific DNA binding and transcriptional modulation in tissue-resident cells. Chitomur-specific molecular characterisation is absent from indexed primary literature; the available evidence concerns clinical-level urodynamic endpoints rather than the molecular mechanism.
Tier 4. The Gomberg 2013 Russian-language clinical report describes a randomized blind trial of chitomur in elderly women with hyperactive bladder, with reduction in urgency and incontinence episodes and improvement in quality-of-life self-assessment. The sample, blinding details, and pharmacovigilance structure fall short of FDA-grade trial standards, and the work has not been independently replicated in Western literature.
The Gomberg 2013 report describes no observed side effects in the studied population. No comprehensive Western post-marketing or pharmacovigilance database exists.
Regulatory status
- FDA status:
- Not FDA-approved
Russian-origin literature (Khavinson group, Saint-Petersburg Institute of Bioregulation and Gerontology) without independent Western replication. The single small clinical study is published in Russian and has not been reproduced or extended by independent labs. Vendor-sold material in the US research-chemical channel is sold against claims of bladder regeneration that the published record cannot support, and buyers cannot cross-check vendor product identity against any pharmaceutical reference standard.